Wednesday, May 2025

03:50 PM - 04:10 PM

Room: LL20D

Session: Emerging Technologies for Medical Applications

Optogenetic Manipulation of Neurons Using Organic Light-Emitting Diodes

Description:

We developed tandem-structured blue and yellow OLEDs optimized for optogenetics, achieving peak optical power densities of ~3.1 mW/mm² and ~3.8 mW/mm², respectively. The emission spectra were matched to the activation spectra of opsins like ChR2 and Arch, enabling effective neuronal activation and inhibition. With a custom-made 64-channel MEA, we demonstrated precise temporal correlations between OLED stimulation and neuronal responses.